منابع مشابه
Neuroprotective Agents in Glaucoma
1.1 Glaucoma as a neurodegenerative disorder Glaucoma is a multifactorial disease in which multiple genetic, systemic and environmental factors interact to precipitate the disease. Increased intraocular pressure (IOP) is believed to be one of the major factors responsible for glaucomatous cell death. (Guo et al., 2005). The axons of the optic nerve make a twisting exit through the fenestrated c...
متن کاملEvidence of the neuroprotective role of citicoline in glaucoma patients.
The glaucomatous disease is currently considered a disease involving ocular and visual brain structures. This new approach to glaucoma introduces the possibility of inducing an improvement by means of a pharmacological approach similar to that used in different degenerative brain disorders. In line with this hypothesis, we studied the effects of oral (1600 mg/die, Cebrolux, Tubilux Pharma, Pome...
متن کاملglaucomatous optic neuropathy management: the role of neuroprotective agents
glaucoma is a major cause of worldwide irreversible blindness. the central role of raised intraocular pressure (iop) is being questioned as many patients continue to demonstrate a clinically downhill course despite initial control of iop. the latest concept of recognizing glaucoma as a multifactorial, progressive, neurodegenerative disease of retinal ganglion cells (rgcss) associated with chara...
متن کاملNeuroprotective therapies for glaucoma
Glaucoma is the second leading cause for blindness worldwide. It is mainly caused by glaucomatous optic neuropathy (GON) characterized by retinal ganglion cell loss, which leads to visual field defect and blindness. Up to now, the main purpose of antiglaucomatous therapies has been to lower intraocular pressure (IOP) through surgeries and medications. However, it has been found that progressive...
متن کاملGlaucomatous Optic Neuropathy Management: the Role of Neuroprotective Agents
Glaucoma is a major cause of worldwide irreversible blindness. The central role of raised intraocular pressure (IOP) is being questioned as many patients continue to demonstrate a clinically downhill course despite initial control of IOP. The latest concept of recognizing glaucoma as a multifactorial, progressive, neurodegenerative disease of retinal ganglion cells (RGCSs) associated with chara...
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ژورنال
عنوان ژورنال: International Journal of Basic & Clinical Pharmacology
سال: 2014
ISSN: 2319-2003
DOI: 10.5455/2319-2003.ijbcp20141016